Potentiating mGluR5 function with a positive allosteric modulator enhances adaptive learning
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چکیده
منابع مشابه
Potentiating mGluR5 function with a positive allosteric modulator enhances adaptive learning.
Metabotropic glutamate receptor 5 (mGluR5) plays important roles in modulating neural activity and plasticity and has been associated with several neuropathological disorders. Previous work has shown that genetic ablation or pharmacological inhibition of mGluR5 disrupts fear extinction and spatial reversal learning, suggesting that mGluR5 signaling is required for different forms of adaptive le...
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ژورنال
عنوان ژورنال: Learning & Memory
سال: 2013
ISSN: 1072-0502,1549-5485
DOI: 10.1101/lm.031666.113